2022

In the last two decades, the pharma industry shifted towards the implementation of green chemistry practices and sustainability strategies, in search of innovative ways to minimize its environmental footprint. Green pharmaceuticals focus on minimizing hazards and pollution while adopting greener drug discovery routes and development practices.

Cyclodextrins are cyclic oligomers of glucose that naturally occur from the enzymatic degradation of the most essential polysaccharides, starch. They have been known for almost 130 years but they really made their breakthrough in the 1980s with the first applications in the pharmaceutical and food industries.

In search of more sophisticated approaches to solvent substitution, Deep Eutectic Solvents (DES) have emerged as an attractive alternative to common organic solvents, due to their cost-effectiveness, simple synthesis, and eco-friendly properties.

Since the introduction of insulin almost a century ago, interest in peptides in pharmaceutical research and development has steadily evolved, establishing their efficacy and wide medicinal potential.